Description

3-Iodothieno[2,3-b]pyridine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a thiophene and a pyridine ring system functionalized with a reactive iodine atom. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry programs targeting novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Ligand Synthesis: Utilized for the preparation of complex ligands used in catalysis and coordination chemistry.
• Chemical Biology: Acts as a probe or a tag in the development of biochemical tools and diagnostic agents.

Basic Information

Product Name	3-Iodothieno[2,3-b]pyridine
CAS No.	53399-37-4
Molecular Formula	C7H4INS
Molecular Weight	260.08 g/mol
Synonyms	3-Iodothieno[2,3-b]pyridine; Thieno[2,3-b]pyridine, 3-iodo-; 3-Iodo-thieno[2,3-b]pyridine; 3-Iodothieno(2,3-b)pyridine; 3-Iodo-thieno[2,3-b]pyridine; 3-Iodothienopyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Iodothieno[2,3-b]pyridine is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.