Description

5',6',7',8'-Tetrahydrodispiro[Cyclohexane-1,2'(3'H)-Quinazoline-4'(4A'H),1''-Cyclohexane] is a complex, high-purity spirocyclic organic compound with the CAS number 53378-71-5. This specialized chemical serves as a critical advanced intermediate or pharmacophore building block in sophisticated organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

This spirocyclic quinazoline derivative is a versatile scaffold with applications in advanced research and development.

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides with unique modes of action.
• Material Science Research: Acts as a precursor for creating specialized organic ligands and functional materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and medicinal chemistry programs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Item	Details
Product Name	5',6',7',8'-Tetrahydrodispiro[Cyclohexane-1,2'(3'H)-Quinazoline-4'(4A'H),1''-Cyclohexane]
CAS No.	53378-71-5
Molecular Formula	C20H28N2
Molecular Weight	296.45 g/mol
Synonyms	5',6',7',8'-Tetrahydrodispiro[cyclohexane-1,2'-[3H]quinazoline-4',1''-cyclohexane]; Dispiro[cyclohexane-1,2'-[3H]quinazoline-4',1''-cyclohexane], 5',6',7',8'-tetrahydro-; Tetrahydrodispiro(cyclohexane-1,2'-[3H]quinazoline-4',1''-cyclohexane); Spirocyclic Quinazoline Derivative; CAS 53378-71-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.