Description

2,6-Dibromo-3-Pyridinecarbonitrile is a halogenated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the bromine atoms offer sites for cross-coupling reactions and the nitrile group provides a handle for further chemical transformations. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for constructing sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized organic molecules for electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form biaryl and other complex structures.
• Nitrile Transformation Chemistry: The cyano group can be hydrolyzed to carboxylic acids, reduced to amines, or used to form heterocycles like tetrazoles and triazoles.

Basic Information

Product Name	2,6-Dibromo-3-Pyridinecarbonitrile
CAS No.	53367-52-5
Molecular Formula	C6H2Br2N2
Molecular Weight	261.90 g/mol
Synonyms	3-Cyano-2,6-dibromopyridine; 2,6-Dibromonicotinonitrile; 2,6-Dibromopyridine-3-carbonitrile; Nicotinonitrile, 2,6-dibromo-; 3-Pyridinecarbonitrile, 2,6-dibromo-
EINECS	Contact for details

Quality Control

Our 2,6-Dibromo-3-Pyridinecarbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.