Description

2-Amino-3-Nitro-5-Trifluoromethylpyridine is a high-value, multi-functional heterocyclic building block distinguished by its unique trifluoromethyl and nitro-substituted pyridine core. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs), where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Serves as a crucial building block for next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals and electronic chemicals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and target engagement.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to specific client R&D projects.

Basic Information

Product Name	2-Amino-3-Nitro-5-Trifluoromethylpyridine
CAS No.	53359-69-6
Molecular Formula	C6H4F3N3O2
Molecular Weight	207.11 g/mol
Synonyms	5-(Trifluoromethyl)-3-nitro-2-pyridinamine; 2-Pyridinamine, 3-nitro-5-(trifluoromethyl)-; 3-Nitro-5-trifluoromethylpyridin-2-amine; 2-Amino-3-nitro-5-(trifluoromethyl)pyridine; 5-Trifluoromethyl-3-nitro-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Nitro-5-Trifluoromethylpyridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete analytical data are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.