Description

1-(2-Hydroxy-4,6-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One is a high-purity synthetic chalcone derivative, a key chemical scaffold valued for its biological activity and utility in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where precise molecular structure is paramount for efficacy. It serves as a vital intermediate for scientists and manufacturers developing novel active ingredients, particularly in drug discovery programs targeting inflammation and metabolic disorders.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those with anti-inflammatory, anticancer, or antimicrobial properties.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chalcone backbone for bioactive molecule design.
• Biochemical Research: Serves as a reference standard or probe in enzymatic studies and pharmacological screening assays.
• Organic Synthesis: Acts as a versatile precursor for synthesizing more complex heterocyclic compounds like flavanones and pyrazolines.
• Material Science Research: Investigated for potential applications in organic electronics and nonlinear optical materials due to its conjugated system.

Basic Information

Product Name	1-(2-Hydroxy-4,6-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One
CAS No.	53350-27-9
Molecular Formula	C20H22O7
Molecular Weight	374.39 g/mol
Synonyms	2',4',6'-Trihydroxy-3,4,5-trimethoxychalcone; 3,4,5-Trimethoxy-2',4',6'-trihydroxychalcone; 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one; NSC 407296; Chalcone derivative 53350-27-9; Trimethoxychalcone derivative; Light yellow crystalline powder (typical description)
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxy-4,6-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.