Description

2-(Methylsulfonyl)Ethyl 4-Nitrophenyl Carbonate is a specialized, high-purity chemical reagent primarily used as an activated carbonate ester in organic synthesis. This compound is valued for its role as a versatile coupling agent and protecting group intermediate, enabling the controlled synthesis of complex molecules. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on peptide chemistry, prodrug development, and advanced material science.

Application

• Peptide Synthesis: Acts as an efficient coupling reagent for the formation of carbonate and carbamate linkages in solid-phase and solution-phase peptide synthesis.
• Prodrug Development: Used to synthesize carbonate-based prodrugs, where the active pharmaceutical ingredient (API) is temporarily masked for improved bioavailability or targeted delivery.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialized polycarbonates and polymeric materials with tailored properties.
• Bioconjugation: Facilitates the stable attachment of drugs, dyes, or other functional molecules to proteins, antibodies, or nanoparticles for diagnostic and therapeutic applications.
• Chemical Intermediate: A key building block in multi-step organic syntheses for pharmaceuticals, agrochemicals, and advanced organic compounds.
• Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-(Methylsulfonyl)Ethyl 4-Nitrophenyl Carbonate
CAS No.	53298-30-9
Molecular Formula	C10H11NO7S
Molecular Weight	289.26 g/mol
Synonyms	4-Nitrophenyl 2-(Methylsulfonyl)ethyl Carbonate; 2-(Methylsulfonyl)ethyl 4-Nitrobenzoate Carbonate; 2-Methanesulfonylethyl 4-Nitrophenyl Carbonate; 4-Nitrophenyl (2-Methanesulfonylethyl) Carbonate; 2-(Methylsulfonyl)ethyl p-Nitrophenyl Carbonate; p-Nitrophenyl 2-(Methylsulfonyl)ethyl Carbonate; MSNP Carbonate; Activated MSNP Ester
EINECS	Contact for details

Quality Control

Every batch of 2-(Methylsulfonyl)Ethyl 4-Nitrophenyl Carbonate is manufactured and tested under strict quality management systems to ensure consistency and reliability for critical applications. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.