Description

(3As,4R,5S,6Ar)-5-(Benzoyloxy)Hexahydro-4-(Hydroxymethyl)-2H-Cyclopenta[B]Furan-2-One is a high-purity, complex organic intermediate of significant interest in advanced synthetic chemistry. This compound matters for its role as a sophisticated chiral building block, enabling the synthesis of structurally complex molecules with high stereochemical fidelity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex small-molecule drugs.
• Asymmetric Synthesis: Utilized as a critical starting material or intermediate in stereoselective synthesis to construct complex molecular architectures.
• Fine Chemical Production: Serves as a building block for the manufacture of specialty and high-value fine chemicals requiring specific stereochemistry.
• Academic & Industrial Research: Employed in chemical research for method development, catalysis studies, and exploring new synthetic pathways.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	(3As,4R,5S,6Ar)-5-(Benzoyloxy)Hexahydro-4-(Hydroxymethyl)-2H-Cyclopenta[B]Furan-2-One
CAS No.	53275-53-9
Molecular Formula	C15H16O5
Molecular Weight	276.29 g/mol
Synonyms	5-O-Benzoyl-4-hydroxymethyl-2,3,3a,4,5,6a-hexahydrocyclopenta[b]furan-2-one; 5-Benzoyloxyhexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one; 4-(Hydroxymethyl)-5-(benzoyloxy)hexahydro-2H-cyclopenta[b]furan-2-one; (3aR,4R,5S,6aS)-5-(Benzoyloxy)hexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one; Cyclopenta[b]furan-2-one derivative; Chiral lactone intermediate.
EINECS	Contact for details

Quality Control

Our (3As,4R,5S,6Ar)-5-(Benzoyloxy)Hexahydro-4-(Hydroxymethyl)-2H-Cyclopenta[B]Furan-2-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to meet rigorous research and development standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.