Description

Pinaverium Bromide is a quaternary ammonium antimuscarinic agent with selective action on the gastrointestinal tract. This pharmaceutical active ingredient is valued for its ability to manage functional bowel disorders by reducing smooth muscle spasms. It is primarily utilized by pharmaceutical manufacturers in the production of prescription medications for treating conditions like irritable bowel syndrome (IBS). Pinaverium Bromide CAS NO 53251-94-8 offers a targeted therapeutic approach with a well-established safety profile.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of prescription drugs for gastrointestinal motility disorders.
• Irritable Bowel Syndrome (IBS) Treatment: Manufacture of tablets or capsules specifically indicated for the relief of abdominal pain, discomfort, and bowel habit changes associated with IBS.
• Symptomatic Relief of Colonopathy: Used in medications targeting symptoms of functional colonic disorders, including spastic colon.
• Gastrointestinal Spasmolytic Agent: Key material in antispasmodic drugs that alleviate cramps and pain caused by smooth muscle contractions in the gut.
• Clinical Research & Development: Serves as a reference standard or raw material in preclinical and clinical studies for new gastrointestinal therapies.
• Drug Product Formulation: Used in the development and scale-up of various solid oral dosage forms, leveraging its compatibility with standard excipients.

Basic Information

Product Name	Pinaverium Bromide
CAS No.	53251-94-8
Molecular Formula	C26H41BrN2O4
Molecular Weight	525.52 g/mol
Synonyms	Pinaverium Bromide; 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-2-norpinyl)ethoxy]ethyl]morpholinium Bromide; Dicetel (Trade Name); Pinaverio Bromuro; Pinaveriumbromid; BR-2511; LA-285; 1-(4,5-Dimethoxy-2-bromobenzyl)-1-[2-(6,6-dimethyl-2-norpinanyl)ethoxyethyl]piperidinium Bromide
EINECS	Contact for details

Quality Control

Our Pinaverium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) are provided, detailing results for identity, purity, and impurity profiles as per in-house specifications. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Solvent Residues (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.