Description

5-Amino-3-Bromo-2-Methoxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a bromo substituent on the methoxypyridine core, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated pyridine scaffold.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials and specialty polymers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry, enabling the exploration of new chemical space and structure-activity relationships.

Basic Information

Product Name	5-Amino-3-Bromo-2-Methoxypyridine
CAS No.	53242-18-5
Molecular Formula	C6H7BrN2O
Molecular Weight	203.04 g/mol
Synonyms	3-Bromo-2-methoxy-5-aminopyridine; 2-Methoxy-3-bromo-5-aminopyridine; 5-Amino-3-bromo-2-methoxypyridine; 3-Bromo-5-amino-2-methoxypyridine; 2-Methoxy-5-amino-3-bromopyridine; 5-Amino-3-bromo-2-pyridinol methyl ether
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Bromo-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.