Description

2-[(6-Methoxypyridin-3-Ylamino)Methylene]Malonic Acid Diethyl Ester is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing pyridine and malonate-derived heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive diethyl malonate moiety.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a starting material for synthesizing electron-transport or emissive layer components in advanced display technologies.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands for transition metal catalysis used in cross-coupling and other organic transformations.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, particularly in annulation and cyclization reactions.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized colorants and functional dyes due to its conjugated system.

Basic Information

Product Name	2-[(6-Methoxypyridin-3-Ylamino)Methylene]Malonic Acid Diethyl Ester
CAS No.	53241-90-0
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	Diethyl 2-[(6-methoxypyridin-3-ylamino)methylene]malonate; 2-[(6-Methoxy-3-pyridinylamino)methylene]malonic Acid Diethyl Ester; (6-Methoxy-3-pyridinylamino)methylene Malonic Acid Diethyl Ester; Propanedioic acid, [(6-methoxy-3-pyridinylamino)methylene]-, diethyl ester; Diethyl (Z)-2-((6-methoxypyridin-3-ylamino)methylene)malonate; Diethyl (amino(6-methoxypyridin-3-yl)methylene)malonate
EINECS	Contact for details

Quality Control

Our 2-[(6-Methoxypyridin-3-Ylamino)Methylene]Malonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and batch-to-batch reproducibility for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents. For long-term storage, consider using an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.