Description

8-Chloro-6-Phenyl-4H-2,3,5,10B-Tetraaza-Benzo[E]Azulene CAS NO 53180-72-6 is a high-purity, complex heterocyclic organic compound characterized by its fused polycyclic structure containing multiple nitrogen atoms. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in therapeutic areas targeting the central nervous system, oncology, and anti-inflammatory applications.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to discover new bioactive molecules.
• Agrochemical Development: Used in research for creating novel herbicides, fungicides, or insecticides, leveraging its complex heterocyclic structure.
• Organic Electronic Materials: Potential precursor for the development of organic semiconductors, light-emitting diodes (OLEDs), or other functional materials due to its conjugated π-system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Catalyst Ligand Synthesis: Can be functionalized to create novel ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	8-Chloro-6-Phenyl-4H-2,3,5,10B-Tetraaza-Benzo[E]Azulene
CAS No.	53180-72-6
Molecular Formula	C19H13ClN4
Molecular Weight	332.79 g/mol
Synonyms	8-Chloro-6-phenyl-4H-2,3,5,10b-tetraazabenzo[e]azulene; Benzo[e]azulene, 8-chloro-2,3,5,10b-tetraaza-6-phenyl-4H-; 8-Chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,8]naphthyridine; 8-Chloro-6-phenyl-[1,2,4]triazolo[4,3-a][1,8]naphthyridine; 4H-2,3,5,10b-Tetraazabenzo[e]azulene, 8-chloro-6-phenyl-; 53180-72-6; 8-Cl-6-Ph-4H-TABA
EINECS	Contact for details

Quality Control

Our 8-Chloro-6-Phenyl-4H-2,3,5,10B-Tetraaza-Benzo[E]Azulene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.