Description

Ethyl 3-Oxo-3-(Thiophen-3-Yl)Propanoate is a high-purity organic ester building block featuring a thiophene moiety, valued for its role as a versatile synthon in advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture to develop novel active compounds. It is primarily utilized in the pharmaceutical and agrochemical sectors for the research and development of new chemical entities, as well as in advanced material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene ring's bioactivity.
• Material Science Research: Serves as a precursor for organic semiconductors, conductive polymers, and other functional materials where the thiophene unit is integral to electronic properties.
• Chemical Research & Development: Employed as a versatile synthon in organic chemistry for constructing complex molecules via reactions like Claisen condensations, Michael additions, and cyclizations.
• Ligand and Catalyst Development: Useful in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, which are fundamental in modern synthetic chemistry.

Basic Information

Product Name	Ethyl 3-Oxo-3-(Thiophen-3-Yl)Propanoate
CAS No.	53090-46-3
Molecular Formula	C9H10O3S
Molecular Weight	198.24 g/mol
Synonyms	Ethyl 3-(3-Thienyl)-3-oxopropanoate; 3-Oxo-3-(thiophen-3-yl)propanoic acid ethyl ester; Ethyl 3-(thiophen-3-yl)-3-oxopropionate; 3-Thiophen-3-yl-3-oxo-propionic acid ethyl ester; Ethyl β-oxo-β-(3-thienyl)propionate; 3-(3-Thienyl)-3-oxopropanoic Acid Ethyl Ester; Acetoacetic acid 3-thienyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Oxo-3-(Thiophen-3-Yl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.