Description

Ethyl 3-(2,5-Dichlorophenyl)-3-Oxopropanoate is a high-purity, versatile organic intermediate characterized by its β-ketoester functional group flanked by a dichlorinated aromatic ring. This compound matters for its critical role as a key building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various heterocyclic compounds and active pharmaceutical ingredients (APIs), particularly those with chlorinated aromatic systems.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides, leveraging the reactivity of the β-ketoester moiety.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and other specialty chemicals where the 2,5-dichlorophenyl group imparts specific properties.
• Academic & Industrial Research: Employed in organic synthesis research for studying Claisen condensation reactions and developing novel catalytic methodologies.
• Material Science Precursor: Potential use in the synthesis of monomers or ligands for advanced polymeric or coordination complex materials.

Basic Information

Product Name	Ethyl 3-(2,5-Dichlorophenyl)-3-Oxopropanoate
CAS No.	53090-44-1
Molecular Formula	C11H10Cl2O3
Molecular Weight	261.10 g/mol
Synonyms	Ethyl 3-(2,5-dichlorophenyl)-3-oxopropanoate; Ethyl (2,5-dichlorobenzoyl)acetate; 3-Oxo-3-(2,5-dichlorophenyl)propanoic acid ethyl ester; Acetoacetic acid, (2,5-dichlorobenzoyl)-, ethyl ester; 2,5-Dichlorobenzoylacetic acid ethyl ester; Ethyl 2,5-dichlorobenzoylacetate; 53090-44-1
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2,5-Dichlorophenyl)-3-Oxopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.