Description

4-[(2-Chloropyridin-3-Yl)Carbonyl]Morpholine CAS NO 53062-98-9 is a high-purity organic building block featuring a chloropyridine core linked to a morpholine ring via a carbonyl group. This compound is a critical intermediate in the synthesis of advanced pharmaceutical compounds and agrochemicals, valued for its precise reactivity and structural versatility. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential precursor for the development of specialty polymers or functional organic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-[(2-Chloropyridin-3-Yl)Carbonyl]Morpholine
CAS No.	53062-98-9
Molecular Formula	C10H11ClN2O2
Molecular Weight	226.66 g/mol
Synonyms	Morpholine, 4-[(2-chloro-3-pyridinyl)carbonyl]-; 2-Chloro-N-morpholin-4-ylnicotinamide; 4-(2-Chloronicotinoyl)morpholine; 2-Chloro-3-morpholin-4-ylcarbonylpyridine; 3-Morpholin-4-ylcarbonyl-2-chloropyridine; (2-Chloropyridin-3-yl)(morpholino)methanone
EINECS	Contact for details

Quality Control

Our 4-[(2-Chloropyridin-3-Yl)Carbonyl]Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.