Description

[2-[Bis(Trimethylsilyl)Amino]-1-[(Trimethylsilyl)Amino]Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a highly functionalized organosilicon compound featuring a unique phosphonic acid ester core protected by multiple trimethylsilyl (TMS) groups. This advanced chemical intermediate is valued for its role as a versatile building block in sophisticated organic synthesis, particularly in the development of novel materials and active pharmaceutical ingredients (APIs). It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecular architectures.

Application

• Advanced Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those requiring phosphorus-containing or silyl-protected functional groups.
• Ligand and Catalyst Development: Used in the preparation of novel ligands for transition metal catalysis and organocatalysts due to its phosphonate and amine functionalities.
• Agrochemical Synthesis: Employed as a building block for creating new-generation herbicides, insecticides, and plant growth regulators with enhanced properties.
• Materials Science Research: Integral in the development of specialty polymers, surface modifiers, and advanced ceramic precursors where precise control of phosphorus and silicon chemistry is required.
• Process Chemistry & Scale-up: Provides a protected, stable form of a reactive phosphonic acid derivative, facilitating multi-step synthesis in both laboratory and pilot plant settings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzymatic activity and biological pathways involving phosphate esters.

Basic Information

Item	Details
Product Name	[2-[Bis(Trimethylsilyl)Amino]-1-[(Trimethylsilyl)Amino]Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	53044-45-4
Molecular Formula	C17H47N2O3P1Si5
Molecular Weight	518.99 g/mol
Synonyms	Phosphonic acid, P-[2-[bis(trimethylsilyl)amino]-1-[(trimethylsilyl)amino]ethyl]-, bis(trimethylsilyl) ester; Tris(trimethylsilyl) [2-[bis(trimethylsilyl)amino]-1-[(trimethylsilyl)amino]ethyl]phosphonate; N,N-Bis(trimethylsilyl)-2-[(trimethylsilyl)amino]-1-(bis(trimethylsilyloxy)phosphoryl)ethan-1-amine; TMS-protected phosphonoethylamine derivative; Silylated Phosphoramidate Ester
EINECS	Contact for details

Quality Control

Every batch of [2-[Bis(Trimethylsilyl)Amino]-1-[(Trimethylsilyl)Amino]Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing including NMR (1H, 13C, 31P), HPLC, and GC analysis to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.