Description

2-[N,n-Di(Trimethylsilyl)Amino]Ethylphosphonic Acid Di(Trimethylsilyl) Ester is a specialized organosilicon compound featuring a unique bifunctional structure that combines silyl-protected amino and phosphonic ester groups. This molecular architecture makes it a valuable silylating agent and versatile synthetic intermediate for constructing complex molecules and modifying surfaces. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise functional group protection and introduction.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring phosphonate or amino acid analogs.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, fungicides, and plant growth regulators with phosphonate moieties.
• Surface Modification Agent: Employed to functionalize silica, glass, or metal oxide surfaces, imparting specific chemical properties for coatings or chromatography media.
• Ligand Precursor in Catalysis: Acts as a precursor for phosphine- or aminophosphonate-based ligands used in homogeneous catalysis.
• Polymer Additive & Modifier: Utilized to introduce functional groups into polymer backbones to alter physical properties like adhesion, flame retardancy, or biocompatibility.
• Protecting Group Chemistry: The trimethylsilyl (TMS) groups effectively protect sensitive amino and phosphonic acid functionalities during multi-step organic syntheses.
• Research & Development: A critical reagent in academic and industrial R&D for exploring new synthetic methodologies and material science.

Basic Information

Product Name	2-[N,n-Di(Trimethylsilyl)Amino]Ethylphosphonic Acid Di(Trimethylsilyl) Ester
CAS No.	53044-44-3
Molecular Formula	C14H38NO3PSi4
Molecular Weight	412.80 g/mol
Synonyms	2-[Bis(trimethylsilyl)amino]ethylphosphonic acid bis(trimethylsilyl) ester; Di(trimethylsilyl) 2-[bis(trimethylsilyl)amino]ethylphosphonate; N,N-Bis(trimethylsilyl)-2-aminoethylphosphonic acid di-TMS ester; ATEP; (2-((Bis(trimethylsilyl)amino)ethyl)phosphonic acid bis(trimethylsilyl) ester; Phosphonic acid, P-[2-[bis(trimethylsilyl)amino]ethyl]-, bis(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our production of 2-[N,n-Di(Trimethylsilyl)Amino]Ethylphosphonic Acid Di(Trimethylsilyl) Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, GC, and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.