Description

[1-[(Trimethylsilyl)Amino]Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is a specialized organosilicon-protected phosphonic acid derivative, serving as a key synthetic intermediate. This compound is valued for its role in introducing the phosphonic acid functional group under mild conditions, offering superior stability and handling compared to its unprotected counterparts. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of bioactive molecules and functional polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting bone diseases or requiring phosphate bioisosteres.
• Agrochemical Synthesis: Serves as a key building block for creating herbicides, plant growth regulators, and other crop protection agents with phosphonate activity.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal catalysis and in the preparation of organometallic complexes.
• Surface Modification Agent: Used to functionalize metal oxides, silica, and other surfaces to impart specific chemical properties for coatings or composite materials.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of flame-retardant polymers, ion-exchange resins, or specialty polyphosphonates.
• Chemical Research & Development: A versatile reagent for organic synthesis, enabling the study of phosphorylation reactions and the creation of complex molecular architectures.

Basic Information

Item	Details
Product Name	[1-[(Trimethylsilyl)Amino]Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	53044-37-4
Molecular Formula	C11H30NO3PSi3
Molecular Weight	339.59 g/mol
Synonyms	Bis(trimethylsilyl) [1-[(trimethylsilyl)amino]ethyl]phosphonate; Phosphonic acid, P-[1-[(trimethylsilyl)amino]ethyl]-, bis(trimethylsilyl) ester; N-(Trimethylsilyl)-1-aminoethylphosphonic acid bis(trimethylsilyl) ester; 1-[(Trimethylsilyl)amino]ethylphosphonic acid bis-TMS ester; ATEP-BTMS; TMS-Protected 1-Aminoethylphosphonate
EINECS	Contact for details

Quality Control

Our production of [1-[(Trimethylsilyl)Amino]Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.