Description

3-(((4-(Bis(2-Chloroethyl)Amino)Phenyl)Acetyl)Oxy)-17A-Aza-D-Homoandrost-5-En-17-One is a sophisticated nitrogen-mustard modified steroidal compound, representing a key intermediate in advanced pharmaceutical research and development. Its molecular architecture, combining a steroidal backbone with a cytotoxic alkylating moiety, makes it a critical building block for the synthesis of targeted anti-cancer agents and other biologically active molecules. This high-purity intermediate is essential for research institutions and pharmaceutical companies focused on oncology, endocrinology, and novel therapeutic modalities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of steroidal alkylating agents and targeted chemotherapeutics.
• Oncology Research: Used in the development and study of novel anti-cancer prodrugs and hormone-targeted therapies.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities (NCEs).
• Bioconjugation Studies: Employed in the creation of steroid-drug conjugates for targeted drug delivery systems.
• Biochemical Tool Compound: Utilized in laboratory research to investigate steroid receptor interactions and signaling pathways.
• API Synthesis: Acts as a key intermediate in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-(((4-(Bis(2-Chloroethyl)Amino)Phenyl)Acetyl)Oxy)-17A-Aza-D-Homoandrost-5-En-17-One
CAS No.	53039-94-4
Molecular Formula	C30H40Cl2N2O3
Molecular Weight	547.56 g/mol
Synonyms	17a-Aza-D-homoandrost-5-en-17-one, 3-(((4-(bis(2-chloroethyl)amino)phenyl)acetyl)oxy)-; 3-[(4-[Bis(2-chloroethyl)amino]benzoyl)oxy]-17a-aza-D-homoandrost-5-en-17-one; Nitrogen Mustard Steroid Conjugate; Steroidal Nitrogen Mustard; Aza-homoandrostane mustard derivative
EINECS	Contact for details

Quality Control

Our 3-(((4-(Bis(2-Chloroethyl)Amino)Phenyl)Acetyl)Oxy)-17A-Aza-D-Homoandrost-5-En-17-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring GMP-grade materials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.