Description

2-(Chloromethyl)Phenyl Isocyanate is a versatile and highly reactive aromatic isocyanate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the dual functionality of the isocyanate and chloromethyl groups, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and polymer industries seeking to develop novel active ingredients and specialty materials.

Application

• Agrochemical Intermediates: Key precursor in the synthesis of novel herbicides, fungicides, and insecticides, where it is used to construct urea and carbamate linkages.
• Pharmaceutical Building Block: Employed in the development of active pharmaceutical ingredients (APIs), particularly for creating urea-based compounds and other heterocyclic structures with biological activity.
• Polymer Modification: Used to introduce reactive isocyanate groups into polymer chains for cross-linking, or to graft functional moieties onto resins and coatings to enhance properties like adhesion and chemical resistance.
• Specialty Chemical Synthesis: Serves as a starting material for synthesizing various fine chemicals, including dyes, pigments, and photoactive compounds.
• Cross-linking Agent: Functions as a cross-linker in the production of polyurethane elastomers, adhesives, and sealants with specific performance characteristics.
• Bioconjugation Chemistry: Utilized in research for labeling biomolecules, where the isocyanate group reacts with amines to form stable urea bonds.

Basic Information

Product Name	2-(Chloromethyl)Phenyl Isocyanate
CAS No.	52986-66-0
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	1-Isocyanato-2-(chloromethyl)benzene; (2-Chloromethyl)phenyl isocyanate; o-(Chloromethyl)phenyl isocyanate; 2-Chloromethylphenyl isocyanate; α-Chloro-o-tolyl isocyanate; NSC 163081; 2-(Chloromethyl)benzenisocyanate
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)Phenyl Isocyanate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.