Description

5-(1-Methylbutyl)-5-Propylbarbituric Acid CAS NO 52944-67-9 is a synthetic barbiturate derivative, a class of compounds historically significant in medicinal chemistry. Its precise chemical structure makes it a valuable intermediate or reference standard for research and development in pharmaceutical synthesis. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of specialized active pharmaceutical ingredients (APIs) and analytical methods.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex barbiturate-based active pharmaceutical ingredients (APIs).
• Chemical Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing via techniques like HPLC and GC.
• Medicinal Chemistry Research: Employed in academic and industrial R&D for structure-activity relationship (SAR) studies related to central nervous system (CNS) agents.
• Biochemical Research: May be used as a tool compound in studies investigating GABAA receptor modulation and related neurological pathways.
• Fine Chemical Synthesis: Acts as a specialized precursor for custom synthesis projects requiring specific barbiturate frameworks.

Basic Information

Product Name	5-(1-Methylbutyl)-5-Propylbarbituric Acid
CAS No.	52944-67-9
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	5-(1-Methylbutyl)-5-propyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Propyl-5-(1-methylbutyl)barbituric acid; 5-Propyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-(1-Methylbutyl)-5-propylbarbituric acid; 5-Propyl-5-(1-methylbutyl)-malonylurea; NSC 172924
EINECS	Contact for details

Quality Control

Our 5-(1-Methylbutyl)-5-Propylbarbituric Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as assay (HPLC), related substances, and residual solvents. We support cGMP compliance for pharmaceutical applications, and specifications can be aligned with client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.