Description

2-(4-Methylpiperazin-1-Yl)Nicotinonitrile is a versatile and high-value pharmaceutical intermediate featuring a substituted nicotinonitrile core. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Chemical Synthesis Reagent: Used in research-scale and process chemistry for constructing heterocyclic compounds and functionalized pyridine derivatives.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Employed in the synthetic route for potential APIs requiring a functionalized piperazinyl-nicotinonitrile moiety.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	2-(4-Methylpiperazin-1-Yl)Nicotinonitrile
CAS No.	52943-14-3
Molecular Formula	C11H14N4
Molecular Weight	202.26 g/mol
Synonyms	2-(4-Methyl-1-piperazinyl)-3-pyridinecarbonitrile; 3-Cyano-2-(4-methylpiperazin-1-yl)pyridine; Nicotinonitrile, 2-(4-methyl-1-piperazinyl)-; 2-(4-Methylpiperazin-1-yl)nicotinonitrile; 2-(N-Methylpiperazino)nicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazin-1-Yl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.