Description

5-Ethyl-5-(1-methylbutyl)-1,3-bis(trimethylsilyl)-2,4,6(1H,3H,5H)-pyrimidinetrione is a specialized silylated barbiturate derivative, a key intermediate in advanced organic synthesis. This compound matters for its role as a protected synthon, enabling precise chemical modifications while safeguarding reactive sites. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel barbiturate analogs and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the pyrimidinetrione core provides specific biological activity.
• Organic Synthesis Reagent: Acts as a versatile protected intermediate for introducing the barbiturate moiety into more complex molecules under mild conditions.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or ligands for metal-organic frameworks (MOFs) due to its silyl protecting groups and heterocyclic structure.
• Academic & Industrial R&D: A valuable tool for methodological studies in synthetic chemistry, particularly in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Ethyl-5-(1-methylbutyl)-1,3-bis(trimethylsilyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS No.	52937-68-5
Molecular Formula	C17H34N2O3Si2
Molecular Weight	370.63 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-ethyl-5-(1-methylbutyl)barbituric acid; 5-Ethyl-5-(1-methylbutyl)-1,3-bis(trimethylsilyl)barbituric acid; 5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxo-1,3-bis(trimethylsilyl)hexahydropyrimidine; 5-Ethyl-5-sec-butyl-1,3-bis(trimethylsilyl)barbituric acid; Silylated secobarbital derivative; TMS-protected barbiturate
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(1-methylbutyl)-1,3-bis(trimethylsilyl)-2,4,6(1H,3H,5H)-pyrimidinetrione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.