Description

5-Ethyl-5-(3-Methylbutyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized silylated barbiturate derivative, a key intermediate in advanced organic synthesis. This compound matters for its role in facilitating complex chemical transformations, particularly in the development of novel pharmaceuticals and high-performance materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a protected or modified barbiturate core for the synthesis of novel central nervous system (CNS) active agents and other therapeutic candidates.
• Advanced Organic Synthesis: Used as a key building block in multi-step syntheses, where the trimethylsilyl (TMS) groups act as protective or directing moieties.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection, leveraging its heterocyclic structure.
• Material Science Precursor: Potential use in the synthesis of organic frameworks or ligands for catalytic systems due to its functionalized pyrimidinetrione core.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of target molecules containing barbiturate-like structures.

Basic Information

Product Name	5-Ethyl-5-(3-Methylbutyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	52937-67-4
Molecular Formula	C₁₈H₃₆N₂O₃Si₂
Molecular Weight	400.67 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-ethyl-5-(3-methylbutyl)barbituric acid; 5-Ethyl-5-(3-methylbutyl)-1,3-bis(trimethylsilyl)barbituric acid; 5-Ethyl-5-(3-methylbutyl)-1,3-bis-O-(trimethylsilyl)barbituric acid; TMS-Barbiturate Derivative; Silylated Barbiturate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(3-Methylbutyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.