Description

5-Ethyl-5-Isopropyl-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-protected derivative of a barbituric acid analog, offering unique reactivity and stability for advanced synthetic chemistry. This compound matters as a versatile building block and protecting group reagent, enabling precise molecular construction in sensitive environments where standard precursors may be unstable. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel heterocyclic compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel central nervous system (CNS) active agents and other therapeutic heterocycles.
• Advanced Organic Synthesis: Acts as a protected precursor or a masked malonamide derivative for constructing complex molecular architectures under anhydrous conditions.
• Agrochemical Research: Utilized in the synthesis of experimental herbicides, insecticides, and plant growth regulators that require specific pyrimidinetrione cores.
• Material Science Precursor: Employed in the development of organic semiconductors, ligands for catalysis, or monomers for specialized polymers.
• Academic & R&D Laboratories: Used as a reference standard and a reagent in methodological studies focusing on silicon-based protective group chemistry and heterocyclic compound formation.

Basic Information

Product Name	5-Ethyl-5-Isopropyl-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	52937-65-2
Molecular Formula	C15H30N2O3Si2
Molecular Weight	342.58 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-ethyl-5-isopropylbarbituric acid; 5-Ethyl-5-isopropyl-1,3-bis(trimethylsilyl)barbituric acid; 5-Ethyl-5-(1-methylethyl-1,3-bis(trimethylsilyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; TMS-protected 5-ethyl-5-isopropylbarbituric acid; N,N'-Bis(trimethylsilyl)-5-ethyl-5-isopropylbarbituric acid; 52937-65-2; 5-Ethyl-5-isopropyl-1,3-di(trimethylsilyl)pyrimidine-2,4,6(1H,3H,5H)-trione
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-Isopropyl-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.