Description

(E)-α-Ethylidenepiperidine-1-Acetaldehyde is a versatile chiral building block and intermediate in organic synthesis. This compound matters for its role in constructing complex nitrogen-containing heterocycles, which are crucial scaffolds in modern pharmaceutical and agrochemical discovery. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the piperidine moiety contributes to biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in asymmetric catalysis and metal complex formation.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating complex, high-value specialty chemicals.
• Academic and R&D: Utilized in university and institutional research for methodological studies in organic chemistry and the exploration of new reaction pathways.

Basic Information

Product Name	(E)-α-Ethylidenepiperidine-1-Acetaldehyde
CAS No.	52900-93-3
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	1-(2-Formylvinyl)piperidine; (E)-1-(2-Formylethenyl)piperidine; 1-(2-Formylvinyl)piperidine; α-Ethylidenepiperidine-1-acetaldehyde; (E)-α-Ethylidenepiperidineacetaldehyde; 2-(1-Piperidinyl)-2-butenal; (E)-2-(Piperidin-1-yl)but-2-enal
EINECS	Contact for details

Quality Control

Our (E)-α-Ethylidenepiperidine-1-Acetaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the stringent requirements of research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.