Description

5-Azaspiro[3.4]Octane is a versatile and highly valuable nitrogen-containing spirocyclic building block. Its unique bridged bicyclic structure makes it a critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with enhanced biological activity and physicochemical properties. This compound is essential for medicinal chemists and R&D professionals in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key scaffold for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and functional organic materials with specific electronic or structural properties.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services catering to advanced R&D projects.

Basic Information

Product Name	5-Azaspiro[3.4]Octane
CAS No.	52876-78-5
Molecular Formula	C7H13N
Molecular Weight	111.18 g/mol
Synonyms	5-Azaspiro[3.4]octane; 1-Azaspiro[3.4]octane; Azaspirooctane; Spiro[cyclopropane-1,4'-piperidine]; 1,4-Diazaspiro[4.4]nonane (isomer); 5-Aza-spiro[3.4]octane; 5-Aza-spiro[3.4]octane hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[3.4]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring reliable and traceable raw materials for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.