Description

3-Amino-2,6-Dibromoisonicotinic Acid is a specialized brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromine and amino functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the dibromo-substituted pyridine core imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors and photoactive materials due to its electron-deficient aromatic system.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	3-Amino-2,6-Dibromoisonicotinic Acid
CAS No.	52834-10-3
Molecular Formula	C6H4Br2N2O2
Molecular Weight	295.92 g/mol
Synonyms	2,6-Dibromo-3-aminopyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 3-amino-2,6-dibromo-; 3-Amino-2,6-dibromo-4-pyridinecarboxylic acid; 2,6-Dibromo-3-aminoisonicotinic Acid; 3-Amino-2,6-dibromopyridine-4-carboxylic Acid; ABDIA; DBAPC
EINECS	Contact for details

Quality Control

Our 3-Amino-2,6-Dibromoisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical use and can tailor specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.