Description

Ethyl 3-p-Tolyloxirane-2-Carboxylate is a high-purity, versatile oxirane (epoxide) derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its ability to introduce functional complexity and stereochemistry into target molecules, enabling the production of high-value fine chemicals and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its oxirane ring can be opened to create molecules with specific modes of action.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and advanced materials that require precise stereochemical control.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in the development and testing of new chiral catalysts and methodologies.
• Polymer Modification: Can be used to introduce reactive epoxide groups into polymer chains for cross-linking or to impart new functional properties to materials.

Basic Information

Product Name	Ethyl 3-p-Tolyloxirane-2-Carboxylate
CAS No.	52788-71-3
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	Ethyl 3-(4-methylphenyl)oxirane-2-carboxylate; Ethyl 3-(p-tolyl)glycidate; Ethyl (2R,3S)-3-(4-methylphenyl)oxirane-2-carboxylate (if stereospecific); Ethyl trans-3-(4-methylphenyl)glycidate; p-Tolyl glycidic acid ethyl ester; 4-Methylphenyl glycidic acid ethyl ester; Oxiranecarboxylic acid, 3-(4-methylphenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-p-Tolyloxirane-2-Carboxylate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.