Description

tert-Butyl (2,2,2-Trifluoro-1-Trifluoromethyl-Ethylidene)-Carbamate is a specialized fluorinated carbamate building block of significant interest in advanced organic synthesis. Its unique structure, featuring a highly fluorinated ethylidene group, makes it a valuable precursor for introducing fluorinated motifs into target molecules, which can dramatically alter their physical and biological properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing lipophilic and metabolically stable fluorinated groups.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where fluorine atoms enhance biological activity and environmental stability.
• Advanced Material Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and other specialty materials with unique surface properties and chemical resistance.
• Medicinal Chemistry Research: A crucial building block for constructing complex molecular architectures in drug discovery programs targeting various disease pathways.
• Process Chemistry & Scale-up: Used in route development and optimization for the commercial manufacturing of fluorinated fine chemicals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring fluorinated intermediates.

Basic Information

Product Name	tert-Butyl (2,2,2-Trifluoro-1-Trifluoromethyl-Ethylidene)-Carbamate
CAS No.	52786-55-7
Molecular Formula	C8H9F6NO2
Molecular Weight	265.15 g/mol
Synonyms	tert-Butyl N-(1,1,1,3,3,3-hexafluoro-2-propanylidene)carbamate; Boc-Hexafluoroisopropylideneamine; N-(tert-Butoxycarbonyl)-1,1,1,3,3,3-hexafluoro-2-propanimine; tert-Butyl (hexafluoroisopropylidene)carbamate; N-Boc-hexafluoroisopropylidenimine; 1,1,1,3,3,3-Hexafluoro-2-[(tert-butoxycarbonyl)imino]propane; Boc-N=C(CF3)2
EINECS	Contact for details

Quality Control

Our tert-Butyl (2,2,2-Trifluoro-1-Trifluoromethyl-Ethylidene)-Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.