Description

Trimethylsilyl 1,2,3,5-Tetrakis-o-(Trimethylsilyl)Hexofuranuronate is a highly functionalized, fully silylated carbohydrate derivative, primarily used as a key protected intermediate in advanced organic synthesis. Its value lies in providing a stable, reactive platform for the selective manipulation of sugar molecules under anhydrous conditions, which is critical for constructing complex oligosaccharides and nucleoside analogs. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex nucleoside analogs, antiviral agents, and other carbohydrate-based therapeutics.
• Oligosaccharide Synthesis: Serves as a protected glycosyl donor or acceptor in the automated or solution-phase synthesis of biologically important oligosaccharides.
• Glycoconjugate Chemistry: Used in the preparation of glycopeptides, glycolipids, and other glycoconjugates for drug discovery and biochemical research.
• Agrochemical Development: Employed as an intermediate in creating novel, sugar-based pesticides or plant growth regulators with specific modes of action.
• Material Science Research: Acts as a precursor for synthesizing functionalized polymers or surfaces with carbohydrate motifs for biosensing or biocompatibility applications.
• Process Chemistry: Utilized in scaling up routes to carbohydrate-active pharmaceutical ingredients (APIs) where precise protection group chemistry is required.

Basic Information

Item	Details
Product Name	Trimethylsilyl 1,2,3,5-Tetrakis-o-(Trimethylsilyl)Hexofuranuronate
CAS No.	52783-57-0
Molecular Formula	C24H56O6Si5
Molecular Weight	609.25 g/mol
Synonyms	1,2,3,5-Tetra-O-trimethylsilyl-α-D-glucofuranuronic acid trimethylsilyl ester; Per-O-trimethylsilyl-D-glucofuranuronic acid trimethylsilyl ester; TMS-Glucofuranuronate, per-O-TMS; Fully silylated D-glucofuranuronic acid TMS ester; 1,2,3,5-Tetrakis-O-(trimethylsilyl)-α-D-glucofuranuronic acid trimethylsilyl ester; α-D-Glucofuranuronic acid, 1,2,3,5-tetrakis-O-(trimethylsilyl)-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our Trimethylsilyl 1,2,3,5-Tetrakis-o-(Trimethylsilyl)Hexofuranuronate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C) and HPLC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and traceability ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent hydrolysis and degradation. Store away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.