Description

2-[(Pyridin-4-Ylmethyl)Sulfanyl]Acetic Acid is a versatile sulfur-containing heterocyclic building block with a pyridine core and a thioether-linked acetic acid moiety. This molecular architecture makes it a valuable intermediate for synthesizing more complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on active ingredients and fine chemicals. The compound's reactivity profile allows for further functionalization, enabling the creation of novel compounds with targeted biological or chemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a functionalized pyridine-thioether scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the sulfur and nitrogen atoms can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating chelating ligands used in homogeneous catalysis and metal complexation studies.
• Bioconjugation and Linker Chemistry: The carboxylic acid group enables its use as a linker molecule in bioconjugation techniques for attaching probes, drugs, or other functional groups to biomolecules.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique electronic or adhesive properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzymatic activity or protein function within biological systems.

Basic Information

Product Name	2-[(Pyridin-4-Ylmethyl)Sulfanyl]Acetic Acid
CAS No.	52758-87-9
Molecular Formula	C8H9NO2S
Molecular Weight	183.23 g/mol
Synonyms	4-[(Carboxymethyl)thio]methylpyridine; (4-Pyridylmethylthio)acetic Acid; 2-[(4-Pyridinylmethyl)thio]acetic Acid; 2-((Pyridin-4-ylmethyl)thio)acetic Acid; 4-Pyridinemethanethiol, S-carboxymethyl derivative; Acetic acid, 2-[(4-pyridinylmethyl)thio]-; 52758-87-9
EINECS	Contact for details

Quality Control

Every batch of 2-[(Pyridin-4-Ylmethyl)Sulfanyl]Acetic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets your research and development specifications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity (by IR and NMR), and related substance profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.