Description

4-Bromomethylphenyl Acetate is a versatile brominated aromatic ester that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in the reactive bromomethyl group, which facilitates efficient functionalization and chain extension in complex molecule construction. This compound is primarily needed by research and development laboratories, pharmaceutical manufacturers, and agrochemical producers for applications in drug discovery, material science, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with substituted aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating specialized aromatic compounds used in electronic displays and optoelectronic devices.
• Polymer & Resin Modification: Employed to introduce brominated aromatic units into polymer chains, enhancing flame retardancy and modifying thermal properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating complex biaryl structures.
• Protecting Group Chemistry: The acetate group can be used for the temporary protection of phenolic hydroxyl groups during multi-step syntheses.
• Chemical Research: A valuable reagent for academic and industrial research in medicinal chemistry and organic methodology development.

Basic Information

Product Name	4-Bromomethylphenyl Acetate
CAS No.	52727-95-4
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	p-(Bromomethyl)phenyl Acetate; 4-(Bromomethyl)phenyl Acetate; 1-(Acetoxymethyl)-4-bromobenzene; Acetic Acid 4-(Bromomethyl)phenyl Ester; [4-(Bromomethyl)phenyl] Acetate; p-Acetoxybenzyl Bromide; 4-Acetoxybenzyl Bromide
EINECS	Contact for details

Quality Control

Our 4-Bromomethylphenyl Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.