Description

Methyl 2-Bromonicotinate is a versatile brominated nicotinate ester, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic reactivity of the bromine atom and ester group, enabling precise functionalization for building complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity building blocks for active ingredient synthesis and novel compound development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for nicotinic acid derivatives and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to synthesize labeled compounds or molecular probes for studying biological pathways.
• Cross-Coupling Reactions: Acts as a reliable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	Methyl 2-Bromonicotinate
CAS No.	52718-95-3
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	2-Bromonicotinic Acid Methyl Ester; Methyl 2-Bromopyridine-3-carboxylate; 3-Pyridinecarboxylic Acid, 2-Bromo-, Methyl Ester; 2-Bromo-3-methoxycarbonylpyridine; 2-Bromopyridine-3-carboxylic Acid Methyl Ester; Nicotinic Acid, 2-Bromo-, Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromonicotinate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities <2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.