Description

4(4-Chlorophenyl)-1-(4-(4-Fluorophenyl)-4-Oxobutyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the synthesis and development of advanced active pharmaceutical ingredients (APIs) targeting specific neurological and psychiatric pathways. It is primarily sought by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly in central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Reference Standard: Serves as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Investigated for its interaction with specific biological receptors and enzymes in pharmacological studies.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Custom Synthesis: Starting material for the preparation of novel derivatives and analogs for patenting and preclinical evaluation.

Basic Information

Product Name	4(4-Chlorophenyl)-1-(4-(4-Fluorophenyl)-4-Oxobutyl)-1,2,3,6-Tetrahydropyridine Hydrochloride
CAS No.	52669-92-8
Molecular Formula	C21H22ClFNO•HCl
Molecular Weight	398.32 g/mol (Free base: 361.86 g/mol)
Synonyms	1-(4-(4-Fluorobenzoyl)butyl)-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride; 4-(4-Chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridine HCl; 52669-92-8; 4-(p-Chlorophenyl)-1-[4-(p-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 4(4-Chlorophenyl)-1-(4-(4-Fluorophenyl)-4-Oxobutyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.