Description

4-Methylcyclophosphamide is a chemically modified derivative of the alkylating agent cyclophosphamide, designed for specialized research and development applications. This compound is valued for its potential as a key intermediate in the synthesis of novel pharmaceutical agents and for advanced biochemical studies. It is primarily utilized by research institutions and pharmaceutical development laboratories focused on oncology and immunology.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of new chemotherapeutic agents and prodrugs.
• Biochemical Research: Used in laboratory studies to investigate alkylating agent mechanisms, metabolism, and structure-activity relationships (SAR).
• Oncology R&D: Employed in the development and screening of novel anti-cancer compounds and targeted therapies.
• Immunology Studies: Applied in research exploring immunosuppressive and immunomodulatory agents.
• Metabolite Analysis: Acts as a reference standard or metabolite analog in analytical method development and pharmacokinetic studies.
• Academic Research: Utilized in university and institutional labs for fundamental chemical and pharmacological research.

Basic Information

Product Name	4-Methylcyclophosphamide
CAS No.	52663-82-8
Molecular Formula	C7H15Cl2N2O2P
Molecular Weight	261.09 g/mol
Synonyms	4-Methylcyclophosphamide; NSC 51325; 4-Methyl Cyclophosphamide; 2-[Bis(2-chloroethyl)amino]-4-methyl-1,3,2-oxazaphosphinane 2-oxide; 4-Methyl-1,3,2-oxazaphosphinane, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide; Cyclophosphamide, 4-methyl-
EINECS	Contact for details

Quality Control

Our 4-Methylcyclophosphamide is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) principles for active pharmaceutical ingredients (APIs) and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require desiccant. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.