Description

n-[3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzoyl]-L-Tyrosine Sodium Salt is a specialized, high-purity synthetic compound designed for advanced research and development applications. This compound is valued for its role as a key intermediate in the synthesis of targeted therapeutic agents, particularly in oncology research. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on developing novel cancer treatments and studying DNA-alkylating agents. Its precise structure makes it a critical building block for creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of experimental anti-cancer agents and targeted therapies.
• Oncology Research: Used in biochemical and pharmacological research to study the mechanisms of DNA alkylation and cell apoptosis.
• Bioconjugation Studies: Serves as a model compound for developing antibody-drug conjugates (ADCs) due to its reactive functional groups.
• Biochemical Tool: Employed in laboratory settings to investigate enzyme interactions and signal transduction pathways related to tyrosine derivatives.
• Preclinical Development: Utilized in the early-stage development and screening of new chemical entities (NCEs) for therapeutic potential.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	n-[3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzoyl]-L-Tyrosine Sodium Salt
CAS No.	52616-30-5
Molecular Formula	C21H23Cl2N3NaO4
Molecular Weight	466.32 g/mol
Synonyms	L-Tyrosine, N-[3-[bis(2-chloroethyl)amino]-4-methylbenzoyl]-, sodium salt; NSC 294721; Sodium N-[3-[bis(2-chloroethyl)amino]-4-methylbenzoyl]tyrosinate; Tyrosine Mustard Derivative Sodium Salt; 4-Methyl-m-LSAR Mustard Tyrosine Conjugate Sodium Salt; N-(3-[Bis(2-chloroethyl)amino]-4-methylbenzoyl)tyrosine sodium salt; CB 3717 Analog
EINECS	Contact for details

Quality Control

Our n-[3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzoyl]-L-Tyrosine Sodium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. Certificates of Analysis (COA) detailing specific lot results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.