Description

n-[3-Bis(2-Chloroethyl)Amino-4-Methylbenzoyl]Glycine Sodium Salt is a specialized organic salt derivative of a nitrogen mustard glycine conjugate, designed for advanced research and development applications. This compound matters for its role as a key synthetic intermediate and a potential precursor in the development of targeted therapeutic agents, particularly in oncology research. It is primarily needed by pharmaceutical R&D laboratories, fine chemical synthesis facilities, and academic institutions focused on medicinal chemistry and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nitrogen mustard-based prodrugs and targeted chemotherapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop compounds with improved efficacy and reduced systemic toxicity.
• Bioconjugation Studies: Acts as a model compound for developing linker technologies in antibody-drug conjugates (ADCs) and other targeted delivery systems.
• Oncology R&D: Investigated as a potential precursor for alkylating agents designed to selectively target cancer cells.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with specific biological activity.
• Biochemical Tool Compound: Utilized in laboratory studies to understand DNA alkylation mechanisms and cellular response pathways.

Basic Information

Product Name	n-[3-Bis(2-Chloroethyl)Amino-4-Methylbenzoyl]Glycine Sodium Salt
CAS No.	52616-26-9
Molecular Formula	C15H19Cl2N2NaO3
Molecular Weight	369.22 g/mol
Synonyms	Glycine, N-[3-[bis(2-chloroethyl)amino]-4-methylbenzoyl]-, sodium salt; Sodium N-[3-[bis(2-chloroethyl)amino]-4-methylbenzoyl]glycinate; NSC 344535; L-Glutamine, N2-[4-methyl-3-[bis(2-chloroethyl)amino]benzoyl]-, sodium salt; 4-Methyl-3-[bis(2-chloroethyl)amino]benzoic acid glycine amide sodium salt
EINECS	Contact for details

Quality Control

Our n-[3-Bis(2-Chloroethyl)Amino-4-Methylbenzoyl]Glycine Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets your research specifications and supports reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.