Description

5-Bromo-2,4-dimethoxypyridine is a versatile halogenated pyridine derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in the strategic positioning of the bromine and methoxy groups, which enable selective functionalization for constructing complex molecular architectures. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its halogenated heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its functionalized pyridine structure.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized pyridine scaffolds.

Basic Information

Product Name	5-Bromo-2,4-dimethoxypyridine
CAS No.	52606-07-2
Molecular Formula	C7H8BrNO2
Molecular Weight	218.05 g/mol
Synonyms	2,4-Dimethoxy-5-bromopyridine; 5-Bromo-2,4-dimethoxypyridine; 5-Bromo-2,4-DMPy; Pyridine, 5-bromo-2,4-dimethoxy-; 5-Br-2,4-Dimethoxypyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-dimethoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.