Description

Methyl 2,3,5-Tri-o-Acetyl-D-Ribofuranoside is a key protected ribofuranoside derivative, serving as a vital chiral building block and synthetic intermediate in organic chemistry. Its primary value lies in providing a selectively acetylated ribose scaffold, which is crucial for the controlled synthesis of nucleoside analogs and other complex biomolecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those developing antiviral agents, anticancer drugs, and novel oligonucleotides.

Application

• Nucleoside & Nucleotide Synthesis: A critical protected intermediate for the controlled synthesis of modified nucleosides and nucleotides.
• Pharmaceutical Intermediates: Used in the research and production of antiviral and anticancer drug candidates.
• Oligonucleotide Chemistry: Serves as a building block for the solid-phase synthesis of RNA analogs and other oligonucleotides.
• Glycosylation Reactions: Acts as a glycosyl donor or acceptor in the synthesis of complex carbohydrates and glycoconjugates.
• Biochemical Research: Employed in studies of enzyme mechanisms and metabolic pathways involving ribose derivatives.
• Fine Chemical Production: A versatile chiral synthon for the preparation of specialty chemicals and advanced materials.

Basic Information

Product Name	Methyl 2,3,5-Tri-o-Acetyl-D-Ribofuranoside
CAS No.	52554-28-6
Molecular Formula	C12H18O8
Molecular Weight	290.26 g/mol
Synonyms	Methyl 2,3,5-Tri-O-acetyl-β-D-ribofuranoside; 1-O-Methyl-2,3,5-tri-O-acetyl-β-D-ribofuranose; Methyl β-D-Ribofuranoside 2,3,5-Triacetate; 2,3,5-Tri-O-acetyl-1-O-methyl-β-D-ribofuranose; β-D-Ribofuranoside, methyl, 2,3,5-triacetate; Methyl Triacetylribofuranoside; Protected Methyl Ribofuranoside
EINECS	Contact for details

Quality Control

Our Methyl 2,3,5-Tri-o-Acetyl-D-Ribofuranoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and chiral analysis, to verify identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.