Description

2-(5H-Chromeno[2,3-B]Pyridin-7-Yl)Acrylic Acid CAS NO 52549-22-1 is a high-purity, synthetically derived organic compound featuring a fused chromenopyridine core linked to an acrylic acid moiety. This specific molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and key building block for complex organic synthesis. It is primarily sought after by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory pathways, and oncological applications.
• Agrochemical Research: Used as a key building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core structure for synthesizing specialized electron-transport or emissive layer materials in display and lighting technologies.
• Coordination Chemistry & Ligand Synthesis: The carboxylic acid and heterocyclic nitrogen atoms provide chelating sites for constructing metal-organic frameworks (MOFs) or catalytic complexes.
• Dye & Pigment Industry: Utilized in the development of advanced chromophores and fluorescent markers for analytical and imaging applications.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	2-(5H-Chromeno[2,3-B]Pyridin-7-Yl)Acrylic Acid
CAS No.	52549-22-1
Molecular Formula	C₁₅H₁₁NO₃
Molecular Weight	253.25 g/mol
Synonyms	7-Acrylic acid-5H-chromeno[2,3-b]pyridine; 2-(5H-Chromeno[2,3-b]pyridin-7-yl)acrylic acid; 5H-Chromeno[2,3-b]pyridine-7-acrylic acid; 7-(2-Carboxyvinyl)-5H-chromeno[2,3-b]pyridine; Chromenopyridine acrylic acid derivative; 52549-22-1 (CAS Name); 2-(5H-Chromeno[2,3-b]pyridin-7-yl)prop-2-enoic acid (IUPAC)
EINECS	Contact for details

Quality Control

Every batch of 2-(5H-Chromeno[2,3-B]Pyridin-7-Yl)Acrylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.