Description

Alfa-Methyl-Alfa-Cyano-5H-[1] Benzopyrano [2,3-B] Pyridine-7-Acetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and cardiovascular pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and novel APIs.
• Organic Synthesis Building Block: Used in research and development for constructing complex benzopyrano-pyridine frameworks.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high-purity, structurally sophisticated intermediates.

Basic Information

Product Name	Alfa-Methyl-Alfa-Cyano-5H-[1] Benzopyrano [2,3-B] Pyridine-7-Acetic Acid Ethyl Ester
CAS No.	52549-16-3
Molecular Formula	C19H16N2O3
Molecular Weight	320.35 g/mol
Synonyms	Ethyl α-Methyl-α-cyano-5H-[1]benzopyrano[2,3-b]pyridine-7-acetate; 7-(Ethoxycarbonylmethyl)-α-methyl-α-cyano-5H-[1]benzopyrano[2,3-b]pyridine; α-Cyano-α-methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid ethyl ester; 52549-16-3; Ethyl 2-cyano-2-methyl-3-oxo-3-(5H-[1]benzopyrano[2,3-b]pyridin-7-yl)propanoate (possible tautomeric form).
EINECS	Contact for details

Quality Control

Our Alfa-Methyl-Alfa-Cyano-5H-[1] Benzopyrano [2,3-B] Pyridine-7-Acetic Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.