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5,5'-Dimethyl-9-Ethyl-3-(2-Hydroxy-Ethyl)-3'-(3-Sulfopropyl)Thiacarbocyanine Betaine CAS NO 52525-52-7


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CAS No.:52525-52-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5,5'-Dimethyl-9-Ethyl-3-(2-Hydroxy-Ethyl)-3'-(3-Sulfopropyl)Thiacarbocyanine Betaine is a high-purity, water-soluble cyanine dye derivative, valued for its excellent photostability and strong near-infrared (NIR) absorption and fluorescence properties. This compound is engineered to provide reliable performance as a key functional component in advanced optical and diagnostic applications. It is primarily needed by manufacturers and research institutions in the biotechnology, medical diagnostics, and materials science sectors for developing sensitive detection systems and functional materials.

Application

  • Fluorescent Labeling and Probes: Used as a covalent label for biomolecules (proteins, nucleic acids) in fluorescence microscopy, flow cytometry, and immunoassays.
  • Optical Imaging Agents: A critical component in the formulation of contrast agents for in vivo and in vitro near-infrared fluorescence (NIRF) imaging.
  • Laser Dye and Photonic Materials: Serves as an active medium in tunable dye lasers and in the development of organic photonic crystals and light-harvesting systems.
  • Sensor Development: Incorporated into chemical and biological sensors for the detection of ions, gases, or specific analytes due to its environment-sensitive fluorescence.
  • Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer in preclinical research for targeted cancer therapies.
  • Non-Linear Optics (NLO): Utilized in research for its potential in frequency doubling and other NLO applications owing to its large molecular polarizability.

Basic Information

Product Name 5,5'-Dimethyl-9-Ethyl-3-(2-Hydroxy-Ethyl)-3'-(3-Sulfopropyl)Thiacarbocyanine Betaine
CAS No. 52525-52-7
Molecular Formula C27H34N2O4S2
Molecular Weight 514.70 g/mol
Synonyms CY7.5 carboxylic acid, sulfonated; Thiacarbocyanine, 5,5'-dimethyl-9-ethyl-3-(2-hydroxyethyl)-3'-(3-sulfopropyl)-, betaine; 3H-Indolium, 2-[5-[1,3-dihydro-3,3-dimethyl-1-ethyl-2H-indol-2-ylidene]-1,3-pentadienyl]-3-ethyl-5-(2-hydroxyethyl)-4-methyl-, sulfate (1:1), inner salt; Sulfocyanine 7.5; NIR-797 analog; Heptamethine cyanine dye sulfonate; Betaine, 5,5'-dimethyl-9-ethyl-3-(2-hydroxyethyl)-3'-(3-sulfopropyl)thiacarbocyanine
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Quality Control

Every batch of our cyanine dyes is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), absorbance/fluorescence maxima, and other critical parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature between 15-25°C (59-77°F) in a dry environment. The product is light-sensitive (store away from light) and should be handled under appropriate conditions to prevent degradation.

Specification

Item Specification
Appearance Dark green to blue-black powder
Identification (HPLC) Conforms to reference standard
Identification (UV-Vis) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Absorption Maxima (λmax) 790 - 810 nm (in suitable solvent)
Emission Maxima (λem) 810 - 830 nm (in suitable solvent)
Solubility Soluble in water, DMSO, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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