Description

2,3,5-Tri-o-Benzyl-1,0-(4-Nitrobenzoyl)-D-Arabinofuranose is a key, high-purity synthetic intermediate in advanced organic chemistry. This compound matters for its critical role in the synthesis of complex nucleoside analogs and other biologically active molecules, where precise stereochemistry and protecting group strategy are paramount. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on antiviral, anticancer, and other therapeutic agent development.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel nucleoside and nucleotide analogs for drug discovery programs.
• Antiviral Pro-drug Synthesis: Used in the development of prodrug forms of antiviral agents, where the protecting groups are strategically cleaved in vivo.
• Carbohydrate Chemistry Research: Serves as a protected arabinofuranose derivative for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Fine Chemical Manufacturing: Employed in the custom synthesis of high-value specialty chemicals for research and development purposes.
• Labeled Compound Synthesis: Acts as a precursor for the preparation of isotopically labeled (e.g., C13, deuterated) compounds for metabolic and pharmacokinetic studies.

Basic Information

Item	Details
Product Name	2,3,5-Tri-o-Benzyl-1,0-(4-Nitrobenzoyl)-D-Arabinofuranose
CAS No.	52522-49-3
Molecular Formula	C33H31NO8
Molecular Weight	569.60 g/mol
Synonyms	1-O-(4-Nitrobenzoyl)-2,3,5-tri-O-benzyl-D-arabinofuranose; 2,3,5-Tri-O-benzyl-1-O-(4-nitrobenzoyl)-D-arabinofuranose; D-Arabinofuranose, 2,3,5-tris-O-(phenylmethyl)-, 1-(4-nitrobenzoate); 2,3,5-Tri-O-benzyl-1-O-(p-nitrobenzoyl)-D-arabinofuranose; 1-O-p-Nitrobenzoyl-2,3,5-tri-O-benzyl-D-arabinofuranose; Protected D-Arabinofuranose Derivative; Benzylated Arabinofuranose Nitrobenzoate
EINECS	Contact for details

Quality Control

Our 2,3,5-Tri-o-Benzyl-1,0-(4-Nitrobenzoyl)-D-Arabinofuranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.