Description

2-Amino-6-Chloronicotinonitrile is a versatile and high-value chemical intermediate characterized by its reactive amino and nitrile functional groups. This compound matters for its critical role in the synthesis of complex heterocyclic structures, particularly in the development of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of various nitrogen-containing heterocycles, such as pyridopyrimidines and triazolopyridines, which are core structures in numerous active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where its chloronicotinonitrile scaffold is valuable for creating compounds with specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed coupling reactions and other advanced synthetic methodologies.
• Material Science Research: Employed in the development of organic electronic materials and functional dyes due to its electron-deficient pyridine core and modifiable functional groups.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Amino-6-Chloronicotinonitrile
CAS No.	52471-07-5
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	6-Chloro-2-aminonicotinonitrile; 2-Amino-6-chloropyridine-3-carbonitrile; 3-Cyano-6-chloropyridin-2-amine; 6-Chloro-2-pyridinamine-3-carbonitrile; 2-Pyridinamine, 6-chloro-3-cyano-; 6-Chloro-3-cyanopyridin-2-amine; 2-Amino-6-chloro-3-cyanopyridine; 6-Chloro-2-amino-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloronicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.