Description

Propargyl-Peg2- Acrylate is a specialized bifunctional monomer featuring both a polymerizable acrylate group and a reactive propargyl group. This unique molecular architecture makes it an essential building block for advanced material synthesis, enabling precise control over polymer architecture and functionality. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as polymer conjugation, hydrogel formation, and the development of functional surfaces.

Application

• Click Chemistry Reagent: Serves as a key component in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Functional Polymer Synthesis: Used to synthesize polymers with pendant alkyne groups for subsequent modification with azide-containing molecules (e.g., drugs, peptides, dyes).
• Hydrogel Fabrication: Employed in the creation of cross-linked hydrogel networks for biomedical applications, including drug delivery systems and tissue engineering scaffolds.
• Surface Modification: Applied to modify material surfaces (e.g., glass, silicon, polymers) to introduce bio-reactive alkyne handles for immobilizing biomolecules.
• Pharmaceutical Intermediates: Acts as a critical intermediate in the synthesis of complex drug molecules and antibody-drug conjugates (ADCs).
• Dendrimer and Star Polymer Construction: Facilitates the synthesis of complex, branched macromolecular structures with controlled functionality.

Basic Information

Product Name	Propargyl-Peg2- Acrylate
CAS No.	52436-42-7
Molecular Formula	C11H16O5
Molecular Weight	228.24 g/mol
Synonyms	2-Methyl-2-propenoic acid 2-[2-(2-propyn-1-yloxy)ethoxy]ethyl ester; Propargyl-PEG2-acrylate; 2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethyl acrylate; Acrylate-PEG2-propargyl; Alkyne-PEG2-acrylate; Propargyloxy-PEG2-acrylate; 2-[2-(Prop-2-yn-1-yloxy)ethoxy]ethyl prop-2-enoate
EINECS	Contact for details

Quality Control

Our Propargyl-Peg2- Acrylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.