Description

2-Amino-6-Chloroisonicotinonitrile is a versatile heterocyclic building block with significant synthetic utility. This compound is valued for its bifunctional reactivity, featuring both an amino group and a nitrile group on a chlorinated pyridine core, enabling its use in constructing complex molecular architectures. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine-based structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Amino-6-Chloroisonicotinonitrile
CAS No.	52413-76-0
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	6-Chloro-2-aminopyridine-4-carbonitrile; 2-Amino-6-chloro-4-cyanopyridine; 6-Chloro-2-aminoisonicotinonitrile; 4-Cyano-6-chloro-2-aminopyridine; 2-Amino-6-chloropyridine-4-carbonitrile; 6-Chloro-2-pyridinamine-4-carbonitrile; 2-Pyridinamine, 6-chloro-4-cyano-
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloroisonicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.