Description

4β-[3-(2-Chloroethyl)-3-Nitrosoureido]Cyclohexane-1α-Acetic Acid is a specialized nitrosourea derivative with significant research and development applications. This compound is valued for its role as a key synthetic intermediate in the development of novel therapeutic agents, particularly in oncology research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential alkylating chemotherapeutic agents and other bioactive compounds.
• Oncology Research: Used in preclinical studies and drug discovery programs targeting cancer cell lines, leveraging its nitrosourea moiety.
• Biochemical Research: Employed as a tool compound in studies investigating DNA alkylation mechanisms and cellular apoptosis pathways.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionalized cyclohexane acetic acid derivatives.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic and medicinal chemistry.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in related API manufacturing.

Basic Information

Product Name	4β-[3-(2-Chloroethyl)-3-Nitrosoureido]Cyclohexane-1α-Acetic Acid
CAS No.	52320-89-5
Molecular Formula	C11H18ClN3O4
Molecular Weight	291.73 g/mol
Synonyms	4β-[3-(2-Chloroethyl)-3-nitrosoureido]cyclohexane-1α-acetic acid; 1-Acetic acid, 4-[3-(2-chloroethyl)-3-nitrosoureido]cyclohexyl-, (1α,4β)-; Cyclohexaneacetic acid, 4-[3-(2-chloroethyl)-3-nitrosoureido]-, (1α,4β)-; 4-[3-(2-Chloroethyl)-3-nitrosoureido]cyclohexylacetic acid; NSC 172112; Nitrosourea CCNU derivative; Lomustine analog intermediate
EINECS	Contact for details

Quality Control

Our 4β-[3-(2-Chloroethyl)-3-Nitrosoureido]Cyclohexane-1α-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.