Description

2',4,4',6'-Tetrahydroxy-3-Methoxychalcone is a specialized polyphenolic chalcone derivative with significant biological and chemical activity. This compound matters for its role as a key intermediate in synthesizing complex flavonoids and as a subject of research in life sciences due to its potential bioactive properties. Industries and research institutions involved in pharmaceutical development, nutraceutical formulation, and advanced organic synthesis require this high-purity chemical for their critical projects.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel flavonoid-based drug candidates and therapeutic agents.
• Biochemical Research: Used as a reference standard and active compound in studies investigating antioxidant, anti-inflammatory, and enzyme inhibition mechanisms.
• Natural Product Synthesis: A key precursor in the laboratory-scale synthesis of complex natural products and their analogues for structure-activity relationship (SAR) studies.
• Cosmeceutical Development: Investigated for potential application in skincare formulations targeting oxidative stress and inflammation due to its polyphenolic structure.
• Analytical Chemistry: Employed as a high-purity standard for method development and calibration in chromatographic analysis (HPLC, LC-MS) of phenolic compounds.

Basic Information

Product Name	2',4,4',6'-Tetrahydroxy-3-Methoxychalcone
CAS No.	52218-19-6
Molecular Formula	C₁₇H₁₆O₇
Molecular Weight	332.31 g/mol
Synonyms	3-Methoxy-2',4,4',6'-tetrahydroxychalcone; 2',4,4',6'-Tetrahydroxy-3'-methoxychalcone; NSC 407303; 1-(2,4-Dihydroxyphenyl)-3-(2,6-dihydroxy-4-methoxyphenyl)-2-propen-1-one; Chalcone, 2',4,4',6'-tetrahydroxy-3-methoxy-; 3'-Methoxy-2,4,4',6-tetrahydroxychalcone
EINECS	Contact for details

Quality Control

Our 2',4,4',6'-Tetrahydroxy-3-Methoxychalcone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.