Description

1H-Pyrazolo[3,4-B]Pyridine-5-Carbonitrile, 6,7-Dihydro-3-Methyl-6-Oxo-1-Phenyl- is a high-purity, heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in medicinal chemistry. Its unique fused pyrazolopyridine core structure makes it a valuable scaffold for the research and development of novel therapeutic agents. This compound is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing novel drug candidates in high-throughput screening libraries.
• Kinase Inhibitor Development: The pyrazolopyridine structure is a privileged motif in the development of protein kinase inhibitors for oncology and inflammatory diseases.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization and the creation of more complex heterocyclic systems.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and pesticides.
• Material Science: Investigated for use in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-5-Carbonitrile, 6,7-Dihydro-3-Methyl-6-Oxo-1-Phenyl-
CAS No.	52217-38-6
Molecular Formula	C14H10N4O
Molecular Weight	250.26 g/mol
Synonyms	1-Phenyl-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile; 6,7-Dihydro-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile; 1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile, 6,7-dihydro-3-methyl-6-oxo-1-phenyl-; 52217-38-6; 1-Phenyl-3-methyl-6-oxo-1,6-dihydropyrazolo[3,4-b]pyridine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazolo[3,4-B]Pyridine-5-Carbonitrile, 6,7-Dihydro-3-Methyl-6-Oxo-1-Phenyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material manufactured under quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.