Description

3-Chloro-2,6-Difluoropyridine is a versatile halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, contributing to enhanced efficacy and selectivity.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated pyridine core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Functional Material Development: Serves as a starting material for creating advanced polymers, liquid crystals, and electronic chemicals.
• Cross-Coupling Reactions: The chloro and fluoro substituents provide distinct reactivity for selective Suzuki, Buchwald-Hartwig, and other metal-catalyzed cross-coupling reactions.
• Chemical Research: A valuable reagent for academic and industrial R&D focused on heterocyclic chemistry and fluorine chemistry.

Basic Information

Product Name	3-Chloro-2,6-Difluoropyridine
CAS No.	52208-56-7
Molecular Formula	C5H2ClF2N
Molecular Weight	149.53 g/mol
Synonyms	2,6-Difluoro-3-chloropyridine; 3-Chloro-2,6-difluoropyridine; Pyridine, 3-chloro-2,6-difluoro-; 3-Chloro-2,6-difluoropyridine (52208-56-7); 2,6-Difluoro-3-chloro-pyridine; 3-Chloro-2,6-difluoro-pyridine; 3-Chloro-2,6-difluoropyridine (CAS 52208-56-7)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,6-Difluoropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.